which girl anime characters are full of win?

All of those are good.

Liru from magipoka and hakufu sonsaku from ikki tousen :P

Rena and Battler from Higurashi no Naku Koro Ni and Umineko no Naku Koro Ni, respectively.

ASD789
If we are talking about this....
Yes she is smoking.

too bad she is fake.

Winry from FMA, definitely. I like how she abuses Ed. Especcially the time she "killed" him with the wrench, his spirit left his body, and Al caught it.